We are frequently told to "take a load off" when things get too much, but when it comes to bone maintenance, doing the opposite can be beneficial. Some important processes for how physical strain induces bone formation have been uncovered by Japanese researchers. Researchers from the National Cerebral and Cardiovascular Center Research Institute have shown that load affects the expression of the peptide osteocrin (OSTN), which increases when load is applied and decreases when it is reduced, in a study that was published in the journal ‘Cell Reports’.
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